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细胞生物学与医学遗传学
 

 

孙玉洁,博士,特聘教授,博士生导师

 
     细胞生物学与医学遗传学系主任
  研究方向:肿瘤分子生物学  
 
 
 

地址:南京市汉中路140号细胞生物学与医学遗传学系

 
 

邮编:210029

 
 

电话:025-86862731

 
 

E-mail:yujiesun@njmu.edu.cn

 


  孙玉洁,女, 特聘教授,博士生导师, 1987年获同济医科大学医学遗传学硕士学位, 同年进入南京医科大学生物教研室工作。1991年赴德国维尔茨堡大学攻读博士学位, 1996年9月获人类遗传学博士学位。 1996年10月赴美国洛杉矶City of Hope National Medical Center工作。2003年元月回国工作,被南京医科大学聘为特聘教授和博士生导师, 细胞生物学和医学遗传学系主任及学科带头人。已发表SCI论文二十余篇,其中近五年发表SCI论文九篇。先后主持承担国家自然科学基金三项、江苏省重点招标项目和江苏省卫生厅科研项目各一项,已招收博士后两人、博士生7名,硕士生12名。目前担任中国环境诱变剂学会理事及致癌专业委员会委员;江苏省遗传学会常务理事及人类遗传学专业委员会副主任。中华医学遗传学杂志编委。主要研究兴趣:(1)原癌基因表达调控的表观遗传学机制;(2)肿瘤转移的分子生物学机制; (3) 乳腺癌细胞对紫杉醇抗性的标志物研究。

Main Publications
1. Gu YM, Tan JX, Lu XW, Ding Y, Han X, Sun Y (2008). BCSG1 methylation status and BCSG1 expression in breast tissues derived from Chinese women with breast cancer. Oncology 74(1-2):61-68.
2. Chen S, Lui J, Li G, Mo F, Xu X, Zhang T, Zhang X,Li J,Han X, Sun Y. (2008). Altered distribution of b-catinin and prognostic roles in colorectal carcinogenesis.Scand J Gastroenterol 43(4):456-464.
3. Joseph-Anthony T. Tan, Yujie Sun, Jing Song, Yuan Chen, Theodore G. Krontiris, and Linda K. Durrin. (2008). SUMO Conjugation to the matrix attachment region-binding protein, special AT-rich sequence-binding protein-1 (SATB1), targets SATB1 to promyelocytic nuclear bodies where it undergoes caspase cleavage. JBC 18124-18134.
4. Changyan Ma, Jingjing Zhang, Linda K Durrin. Jinghuan Lv, Dongya Zhu Xiao Han, and Sun Y.(2007). The BCL2 major breakpoint region (mbr) regulates gene expression. Oncogene 19; 26 (18): 2649-57.
5. Zhang JJ,Ma CY, Han X,Durrin L, and Sun Y.(2006). The BCL2 major breakpoint region (mbr) possesses transcriptional regulatory function. Gene 379:127-13
6. Men Z, Sun J, Ling J, Lv J, Zhu DY, Chen Q, Sun Y* and Han X*.(2006) Prostaglandin E2 regulates Foxo activity via the Akt pathway: implications for pancreatic islat beta-cell dysfunction. Diabetologia 49: 2959-2968. *Co-corresponding authors.
7. Sun Y, Wang T,Yin Y, Xu S, Ma C, Han X.(2006). The behavior of SATB1, a MAR binding protein, in response to apoptosis stimulation. Cell Biology International. 30(3):244-247.
8. Wang Z, Lv JH, Zhang RH, ZyX, Sun Y*, Zhu J, Han X*. (2006). Co-culture with fat cells induces insulin resistance in primary hepatocytes. BBRC 345 (3):976-83. *Co-corresponding authors.
9. Lin J, Sun Y, Zhu D, Chen Q and Han X. Potential role of NO in modulation of COX-2 expression and PGE2 production in pancreatic β-cells. (2005). Acta Biochimica et Biophysica Sinica 37(2):139-146.
10. Sun Y, Durrin, LK, Krontiris TG. (2003). Specific interaction of PML bodies with the TP53 locus in Jurkat Interphase Nuclei. Genomics 82(2):250-258.
11.Sun Y, Wyatt RT, Bigley A, Krontiris TG. (2001). Expression and replication timing patterns of wild type and translocated BCL2 genes. Genomics 73(2): 161-170.


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